Epidemiological and Clinical Profile of HIV-Positive Patients Monitored at the General Hospital of Benguela – Angola, from January to December 2023

Autores

  • Daniel Tavares Núcleo de Investigação Científica dos Estudantes de Saúde de Angola; ⁠Faculdade de Medicina, Universidade Katyavala Bwila
  • Mikah’L Bastos Faculdade de Medicina, Universidade Katyavala Bwila, Huila, Angola
  • Benzildo Santos Faculdade de Medicina, Universidade Katyavala Bwila, Huila, Angola
  • Fernando Quilezi Universidade Katyavala Bwila, Huila, Angola
  • Eládio Palanca Núcleo de Investigação Científica dos Estudantes de Saúde de Angola; ⁠Faculdade de Medicina, Universidade Katyavala Bwila, Huila, Angola
  • Belchior Nunes Núcleo de Investigação Científica dos Estudantes de Saúde de Angola; ⁠Faculdade de Medicina, Universidade Katyavala Bwila, Huila, Angola
  • João Leornado Núcleo de Investigação Científica dos Estudantes de Saúde de Angola; ⁠Faculdade de Medicina, Universidade Katyavala Bwila, Huila, Angola
  • Benedita Tambué Núcleo de Investigação Científica dos Estudantes de Saúde de Angola; Hospital Materno-Infantil Dr. Manuel Pedro Anzacot de Menezes, Luanda, Angola
  • José Frank Lourenço Núcleo de Investigação Científica dos Estudantes de Saúde de Angola; Hospital Geral Heróis de Kifangondo do Cacuaco, Luanda, Angola
  • Jossemy Diakanga Núcleo de Investigação Científica dos Estudantes de Saúde de Angola; ⁠Faculdade de Medicina, Universidade Agostinho Neto, Luanda, Angola
  • Paulo Ney Solari Núcleo de Investigação Científica dos Estudantes de Saúde de Angola; National School of Public Health - NOVA University of Lisbon, Lisbon, Portugal

DOI:

https://doi.org/10.70360/rccse..v.157

Palavras-chave:

HIV, opportunistic infections, tuberculosis, outpatient care, Angola, antiretroviral therapy

Resumo

Introduction: HIV infection compromises the immune system, increasing susceptibility to opportunistic infections such as tuberculosis. This study analyzes the epidemiological and clinical profile of HIV-positive patients at the General Hospital of Benguela, Angola, during 2023. Methods: A descriptive, cross-sectional study was conducted with 229 HIV-positive patients monitored at the General Hospital of Benguela. Data were collected from hospital records, including demographic information, comorbidities, disease stages according to WHO classification, and treatment outcomes. SPSS software was used for statistical analysis, with frequency and percentage distributions for the variables. Results: Among the patients, 43.2% were aged between 18-35 years, and 56.8% were female. The prevalence of comorbidities was significant, with 30% presenting tuberculosis and 39.3% other opportunistic infections. Most patients (65.9%) were in WHO stages II and III, and 79.5% were managed on an outpatient basis, suggesting a stable clinical profile for most. Conclusion: The findings highlight the importance of continuous antiretroviral therapy (ART) and preventive treatment for opportunistic infections in maintaining a stable health status in HIV-positive individuals. Public health policies that ensure consistent access to ART and preventive care are essential for controlling disease progression and transmission.

Referências

(1) Kumah E, Boakye DS, Boateng R, Agyei E. Advancing the Global Fight Against HIV/Aids: Strategies, Barriers, and the Road to Eradication. Ann Glob Health. 89(1):83.

(2) HIV.gov [Internet]. [citado 28 de janeiro de 2025]. HIV and AIDS Epidemic Global Statistics. Disponível em: https://www.hiv.gov/hiv-basics/overview/data-and-trends/global-statistics

(3) regional_fs_latin_america.pdf [Internet]. [citado 28 de janeiro de 2025]. Disponível em: https://thepath.unaids.org/wp-content/themes/unaids2023/assets/files/regional_fs_latin_america.pdf

(4) Zuma K, Simbayi L, Zungu N, Moyo S, Marinda E, Jooste S, et al. The HIV Epidemic in South Africa: Key Findings from 2017 National Population-Based Survey. Int J Environ Res Public Health. 1 de julho de 2022;19(13):8125.

(5) Haeuser E, Serfes AL, Cork MA, Yang M, Abbastabar H, Abhilash ES, et al. Mapping age- and sex-specific HIV prevalence in adults in sub-Saharan Africa, 2000-2018. BMC Med. 19 de dezembro de 2022;20(1):488.

(6) Probst C, Parry CDH, Rehm J. Socio-economic differences in HIV/AIDS mortality in South Africa. Trop Med Int Health TM IH. julho de 2016;21(7):846–55.

(7) Springfield O, Brouwer KC, Avila-Rios S, Morales-Miranda S, Mehta SR. Molecular epidemiology of HIV-1 among adult female sex workers at the Guatemala-Mexico border. Glob Public Health. janeiro de 2023;18(1):2278873.

(8) Ramos NNV, Fronteira I, Martins M do RO. Comprehensive Knowledge of HIV and AIDS and Related Factors in Angolans Aged between 15 and 49 Years. Int J Environ Res Public Health. 23 de setembro de 2023;20(19):6816.

(9) Sebastiao CS, Samulengo J, Paixao J, Sacomboio E, Mateus A, David Z, et al. Risk Factors Related to HIV Infection among TB Patients in Luanda, Angola. J Infect Dis Diagn. 30 de janeiro de 2023;8(3):1–5.

(10) Sebastião CS, Morais J, Brito M. Factors Influencing HIV Drug Resistance among Pregnant Women in Luanda, Angola: Findings from a Cross-Sectional Study. Trop Med Infect Dis. março de 2021;6(1):29.

(11) Sebastião CS, Morais J, Brito M. Clinical and Public Health Implications of HIV- Genetic Diversity and Drug Resistance Mutations in Angola: A Systematic Review. AIDS Rev. 26 de outubro de 2020;23(1):48–56.

(12) Afonso JM, Bello G, Guimarães ML, Sojka M, Morgado MG. HIV-1 Genetic Diversity and Transmitted Drug Resistance Mutations among Patients from the North, Central and South Regions of Angola. PLOS ONE. 29 de agosto de 2012;7(8):e42996.

(13) Sebastião CS, de Morais J, Brito M. Clinical and Public Health Implications of HIV-1 Genetic Diversity and Drug Resistance Mutations in Angola: A Systematic Review. Aids Rev [Internet]. 2021 [citado 28 de janeiro de 2025];23(1). Disponível em: https://www.aidsreviews.com/resumen.php?id=1547&indice=2021231&u=unpZerdali

(14) E, Nakir IY, Sayili U, Sürme S, Yildırım M. Epidemiological and Clinical Profile of Newly Diagnosed HIV/AIDS Patients: A Retrospective Analysis of Changing Trends Over 16 Years. Curr HIV Res. 2023;21(1):35–42.

(15) Dias RFG, Bento LO, Tavares C, Ranes Filho H, Silva MAC da, Moraes LC, et al. Epidemiological and clinical profile of HIV-infected patients from Southwestern Goias State, Brazil. Rev Inst Med Trop São Paulo. 19 de julho de 2018;60:e34.

(16) Bassandja O, Yakusu I, Bongenya B, Kamangu E, Apalata T. [Epidemiological, Clinical And Therapeutic Profile Of Hiv-Infected Patients On Antiretroviral Treatment In Kisangani, Democratic Republic Of Congo]. Mali Med. 2022;38(2):6–9.

(17) Barongo LR, Borgdorff MW, Mosha FF, Nicoll A, Grosskurth H, Senkoro KP, et al. The epidemiology of HIV-1 infection in urban areas, roadside settlements and rural villages in Mwanza Region, Tanzania. AIDS Lond Engl. dezembro de 1992;6(12):1521–8.

(18) Zenner D, Tomkins S, Charlett A, Wellings K, Ncube F. HIV prone occupational exposures: epidemiology and factors associated with initiation of post-exposure pro-phylaxis. J Epidemiol Community Health. maio de 2009;63(5):373–8.

(19) Gupta A, Anand S, Sastry J, Krisagar A, Basavaraj A, Bhat SM, et al. High risk for occupational exposure to HIV and utilization of post-exposure prophylaxis in a teaching hospital in Pune, India. BMC Infect Dis. 21 de outubro de 2008;8:142.

(20) Viana GM de C, Silva MACN da, Garcia JV de S, Guimarães HD, Arcos GF, Santos AVA, et al. Epidemiological profile of patients co-infected with visceral leishmaniasis and HIV/AIDS in Northeast, Brazil. Rev Soc Bras Med Trop. outubro de 2017;50:613–20.

(21) Hasslocher-Moreno AM, Sousa AS de, Xavier SS, Mendes F de SNS, Nunes EP, Grinsztejn BGJ, et al. Epidemiological-clinical profile and mortality in patients coinfect-ed with Trypanosoma cruzi/HIV: experience from a Brazilian reference center. Rev Soc Bras Med Trop. 2022;55:e02402022.

(22) Amadou MLH, Abdoulaye O, Amadou O, Biraïma A, Kadri S, Amoussa AAK, et al. [Epidemiological, clinical and evolutionary profile of patients with tuberculosis at the Regional Hospital of Maradi, Republic of the Niger]. Pan Afr Med J. 2019;33:120.

(23) François Anicet OA, Kouanfack C, Dama U, Nkfusai CN, Abanda JN, Tchoffo D, et al. Prevalence, Epidemiological, and Clinical Profile of Patients Coinfected with Human Immunodeficiency Virus and Tuberculosis in the Coronavirus Disease 2019 Context in Health Facilities in the East Region, Cameroon. Int J MCH AIDS. 2024;13:e006.

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Publicado

04-07-2025

Como Citar

Tavares , D., Bastos, M., Santos, B., Quilezi , F., Palanca , E., Nunes, B., … Solari, P. N. (2025). Epidemiological and Clinical Profile of HIV-Positive Patients Monitored at the General Hospital of Benguela – Angola, from January to December 2023. Revista Científica Da Clínica Sagrada Esperança, (Número 13. Ano 17. JULHO 2025), 32–37. https://doi.org/10.70360/rccse.v.157